People with weakened immune systems are at higher risk of getting severely sick from SARS-CoV-2. Because of this, they have the infection for a longer period of time due to their immune system not fighting it off as fast. If you are immunocompromised, the best way to prevent COVID-19 is to avoid being exposed to this virus. Precautions such as washing hands, cleaning surfaces have to be done more frequent for people with suppresed immune systems.