a group of G protein-coupled receptor and ligand-gated ion channels found in the central and peripheral nervous systems. Serotonin Receptors mediate both excitatory and inhibitory neurotransmission.

Serotonin Receptors

A common example of an indolamine monoamine neurotransmitter.  It's IUPAC name is 5-hydroxytryptamine. Serotonin affects mood, sleep, cognition, learning, reward, memory, and many other behaviors, as well as physiological processes.

Michigan State University

- Class of monoamines derived from amino acid tryptophan
- Contains a five-sided indole ring in the structure
- Includes Melatonin and Serotonin 

Indoleamine Neurotransmitters 

Meinhardt MW, Sommer WH. Schrooms against booze: Potential of mycotherapy for the treatment of AUD. Neuropsychopharmacology. 2022 Sep 8. doi: 10.1038/s41386-022-01446-7. Epub ahead of print. PMID: 36076019.

Schrooms against booze: Potential of mycotherapy for the treatment of AUD

- Abbreviated 5-HT from chemical name 5-hydroxytryptamine 
- Synthesized from the tryptophan amino acid tryptophan, which is only obtained from diet.
- Produced and concentrated in the raphe nuclei of the midbrain and brainstem 
- About 200,000/80 to 90 billion neurons are serotonergic but they exert influence throughout the entire brain 
- Controls sleep states, mood, sexual behavior, and anxiety 
- At least 14 types of serotonin receptors (all but one is metabotropic) 
-Precursor to melatonin

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