The spleen filters and stores blood and immune factors and removes damaged red blood cells. It is a critical site for B and T cell activation as it contains crucial antigen presenting cells like macrophages and dendritic cells.

- Heart
- Arteries
- Veins
- Capillaries
- Kidneys
- Liver
- Spleen

Organs and Vessels of the Circulatory System

Secondary Lymphoid Tissues

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The heart receives deoxygenated blood through the superior/inferior vena cavas and into the right atrium. The blood next passes through the tricuspid valve to enter the right ventricle, where the heart pumps it towards the lungs to be oxygenated. The blood returns to the heart and oxygenated blood is received at the left atrium and flows to the left ventricle. When the heart contracts, the oxygenated blood is pumped throughout the body. 

The Heart

Arteries carry blood away from the heart. It is typically oxygenated blood, except for the pulmonary artery. The largest artery is the aorta.

Arteries

Veins carry blood towards the heart. The blood is usually deoxygenated except for in the pulmonary veins.

Veins

Capillaries are the small vessels where oxygen and nutrient exchange occurs. They exist between arterioles and venules.

Capillaries

The liver filters the blood and removes damaged or defective red blood cells.

The Livers Role in the Circulatory System

Spleen

Lymph nodes contain B and T cell germinal centers and antigen presenting cells like dendrites and macrophages. these lymphocytes come in contact with draining lymph from afferent sites through nearby lymphatic vessels. 

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