Read the following scenario. Based on the information provided, identify three distinct symptoms described that are used in diagnosing a serious mood disturbance, aside from a persistently sad mood or a lack of pleasure in activities.

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Beyond the core symptoms of depressed mood and loss of interest, a diagnosis of major depressive disorder considers several other indicators. These include: significant changes in weight or appetite, sleep disturbances (insomnia or hypersomnia), observable psychomotor changes (agitation or retardation), persistent fatigue, feelings of worthlessness or excessive guilt, difficulty with concentration or decision-making, and recurrent thoughts of suicide.

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