University of South Florida

- The mean time between the onset of symptoms and the initiation of treatment was 4.9 days
- A total of 79/80 patients received treatment on a daily basis throughout the whole study period 
- (65/80, 81.3%) of patients had favorable outcome and were discharged from our unit at the time of writing with low NEWS scores (61/65, 93.8%) 
-A significant decrease of nasopharyngeal viral load tested by qPCR was noted,
with 83% negative at Day7, and 93% at Day8
- The number of patients contagious (with a PCR Ct value < 34) steadily decreased overtime and reached zero on Day 12
- mean time from initiation to discharge was 4.1 days with a mean length of stay of 4.6 days, for the 65 patients who were discharged during the study period

Results: Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study

Gautret, P., Lagier, J., Parola, P., Hoang, V. T., Meddeb, L., Sevestre, J., et al.  (2020). Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study. Travel Medicine and Infectious Disease, 34(SI), 101663. doi:10.1016/j.tmaid.2020.101663
https://www.sciencedirect.com/science/article/pii/S1477893920301319

Clinical and microbiological effect of a combination of Hydroxychloroquine and Azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study

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