Members of the independent review board may lack specialized knowledge to accurately evaluate research that involves the participation of vulnerable populations. 

Cedarville University

A review by individuals unfamiliar with the research. Consists of reviewing the research trial design, the proposed participant selection, and it's risk-benefit ratio.

Independent Review Boards

Raskoff, S. Z., Thurm, A., Miguel, H. O., Kim, S. Y. H., & Quezado, Z. M. N. (2023). Pain research and children and adolescents with severe intellectual disability: ethical challenges and imperatives. The Lancet. Child & adolescent health, 7(4), 288–296. https://doi.org/10.1016/S2352-4642(22)00346-7

Pain research and children and adolescents with severe intellectual disability: ethical challenges and imperatives

The Drawbacks of Independent Review Boards

The minimization risks and enhancement of potential benefits. Research should only expose participants to risks (eg. psychological, physical, or economic burdens) that are necessary to obtain the relevant scientific data.

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