Concept

There was no significant difference between the clinical status of patients in the treatment groups and those in the control group after 7 or 15 days

Participants were randomly assigned to one of three groups: the standard care, hydroxychloroquine (400 mg twice per day for 7 days) and azithromycin (500 mg once per day 7 days) group, the standard care and hydroxychloroquine only group, or the standard care only (control) group. A six-point ordinal scale, with the severity of outcomes increasing from 1 to 6, was used to quantify the clinical status of patients at day 7. There was no significant between-group difference in the outcomes. Then, a seven-point ordinal scale, 7 being the most severe outcome, was used to assess the clinical status of patients at day 15. The figure illustrates the lack of significant difference between the score distributions of the three groups at day 15 (p=1.00). Patients in the control group were less likely to experience adverse events.

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Updated 2020-07-24

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences