TMPRSS2 is most highly expressed in the prostate. It is also very highly expressed in the lungs, bladder, skin, liver, pituitary, and the stomach.

High TMPRSS2 Expression

There is low levels of TMPRSS2 expression seen in locations such as the ovary, heart, arteries, adipose tissue, and most parts of the nervous system.

Low TMPRSS2 Expression

- High TMPRSS2 Expression
- Low TMPRSS2 Expression

Grand Valley State University

This graph displays the variance in the amount of TMPRSS2 expression there is in different types of tissues within the human body.

Graph of the Expression of TMPRSS2 in Various Tissues

Baughn, L. B., Sharma, N., Elhaik, E., Sekulic, A., Bryce, A. H., & Fonseca, R. (2020). Targeting TMPRSS2 in SARS-CoV-2 Infection. Mayo Clinic Proceedings, 95(9), 1989–1999. https://doi.org/10.1016/j.mayocp.2020.06.018.

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