Type II Hypersensitivities are also known as cytotoxic hypersensitivities. Cytotoxic hypersensitivity occurs when a IgM and IgG antibodies interact with cellular antigens. These interactions may activate the Complement System or antibody-dependent cell-mediated cytotoxicity with cytotoxic T cells.

Austin Community College

The four types of hypersensitivity reactions are classified by their specific immune mechanism:
- Type I
- Type II
- Type III
- Type IV

Types of Hypersensitivity

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

OpenStax Microbiology Textbook

Type 1 Hypersensitivities occur when an IgE antibody reacts with an allergen and triggers mast  cell degranulation. Allergens can range from harmless substances such as pollen to hazardous substances such as insect venom or even food intolerances. 

Type 1 Hypersensitivity

Type II (Cytotoxic) Hypersensitivities

Type III Hypersensitivities involve the interactiosn of IgM, IgG, and sometimes IgA antibodies with antigen to form immune complexes. The accumulation of these immune complexes within tissue can lead to tissue damage.

Type III Hypersensitivity

Type IV hypersensitivities occur when activated macrophages or cytotoxic T cells  lead to tissue damage. 

Learn Before

Related