Te EC50 is the concentration of a drug or other compound that causes a response that is halfway between the baseline and maximum after a desired exposure time. It is commonly referred to as the concentration required to obtain 50% of the effect. It is a good empirical value of the potency of the compound.  

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Important Values to Define when Discussing Protease Inhibitors

Wikipedia

- IC50 is one of the most often used measures of how potent a drug can inhibit a certain biological process. IC50 is the half-maximal inhibitory concentration, meaning it is the concentration of the drug needed to inhibit 50% of the biological process. The lower the IC50, the stronger the inhibitor is.

What is IC50?

The Kd is the binding constant, a unit of measurement that demonstrates how tightly a ligand binds to a protein. The lower the Kd value, the tighter the bond is between the ligand and the protein. 

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