-  In a review of 178 children with cancer from a single institution in New York City, 20 tested positive for SARS-CoV-2, and only one required admission (noncritical) for symptoms related to COVID-19. COVID-19 was similarly mild in small surveys of children who developed COVID-19 while receiving immunosuppressive medications for kidney disease or inflammatory bowel disease 
-  In multicenter studies of children admitted to pediatric ICUs, most children had one or more underlying conditions
-  Among children hospitalized with COVID-19 from 14 states by late July 2020, 42 percent had ≥1 underlying condition, the most common of which were obesity (38 percent of children ≥2 years), chronic pulmonary disease (18 percent), and prematurity (15 percent of children <2 years) 

Ohio State University, Columbus

-  Medical complexity
-  Congenital heart disease
-  Neurologic, genetic, or metabolic conditions
-  Chronic kidney disease

-  Immune compromise from solid organ transplant

 -  Obesity

-  Sickle cell disease

-  Type 2 diabetes mellitus
Cerebrovascular disease

-  Chronic pulmonary disease (eg, cystic fibrosis, moderate to severe asthma, pulmonary fibrosis)

-  Hypertension
-  immune compromise from hematopoietic cell transplant, primary immune deficiency, HIV, medications (eg, glucocorticoids)

-  Liver disease

-  Pregnancy

-  Smoking

-  Thalassemia

-  Type 1 diabetes mellitus

Risk factors for severe disease

Deville, J. (2020, August 7). Coronavirus disease 2019 (COVID-19): Clinical manifestations and diagnosis in children. Retrieved August 13, 2020, from https://www.uptodate.com/contents/coronavirus-disease-2019-covid-19-clinical-manifestations-and-diagnosis-in-children?topicRef=127535

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