- 1.Zinc improves the structure of cilia, increasing their functioning; zinc allows more tight junctions form, which can help prevent virus entry
- 2.Zinc prevents the SARS-CoV-2 virus from binding to the ACE2 receptors; zinc inhibits RdRp from being transcribed
- 3.Zinc increases IFNa actions, forming more antiviral proteins
- 4.Zn inhibits IKK action, reucing inflammation
- 5.Zinc prevents bacterial growth

Michigan State University

- Zn2+ may have an anti-inflammatory effect on the lungs of those with pneumonia
- In a study done on rats, those that were lacking zinc ended up have increased expression of proinflammatory receptors, resulting in lung damage
- Hyperoxia can be regulated to prevent lung injury though the zinc and nitric oxide pathways
- Zn can lower neutrophil count in the lowering the chances of acute lung injury
- Zn inhibited phagocyte action
- Zinc can prevent bronchiolitis, bronchitis, and pneumonitis in children
- Patients with sepsis have low serum Zn concentration, increasing cytokine production and the likelihood of inflammation

Zn and lung tissue

Skalny, A. V., Rink, L., Ajsuvakova, O. P., Aschner, M., Gritsenko, V. A., Alekseenko, S. I., ... & Tsatsakis, A. (2020). Zinc and respiratory tract infections: Perspectives for COVID‑19. International Journal of Molecular Medicine, 46(1), 17-26.

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