In a study, the most aggressive monkeys had the lowest levels of serotonin metabolites, which means they had the least serotonin released; mice with one of the serotonin receptor knocked out are hyper-aggressive; inhibitory role

Negative correlation between serotonin and aggression

The balance between inhibitory neurotransmitter GABA and excitatory neurotransmitter glutamate appears to be important in aggressive response to stimuli; antiaggression treatment based on these research

GABA and aggression

experiments on mice: stimulate neurons in this area, the male mice would stop mounting a receptive female mice and start to attack her

Ventromedial hypothalamus (VMH) and aggression

Aggressive behavior is modulated by neurotransmitter systems.
- Negative correlation between serotonin and aggression
- GABA and aggression
- Ventromedial hypothalamus (VMH)

University of Michigan - Ann Arbor

- Aggression
- Androgens seem to increase aggression
- Aggression has several neurochemical correlates
- A topic of controversy

Neural circuitry of violence and aggression

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

Behavioral Neuroscience 8th Edition

Androgens are hormones that contribute to growth and reproduction in both men and women
- Androgen and aggression in animals
- Androgen and aggression in humans
- Some complicated variables in the relationship between androgens and aggression

Androgens seem to increase aggression

Aggression has several neurochemical correlates

- A controversy: some intense violence are derived from temporal lobe disorders (emotional dyscontrol syndrome)
- psychopath
- Biological studies of aggression are controversial

A topic of controversy

Aggression is defined as any behavior intended to cause harm or pain to another person. It is a core topic in social psychology, encompassing a range of actions with different underlying motivations.

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