Allosteric Inhibition Diagram (Figure 8.9a). Reprinted from OpenStax Microbiology (p. 300), by N. Parker, M. Shneegurt, A.-h. Thi Tu, B. M. Forester, and P. Lister, 2016, Rice University. Copyright 2016 by Rice University.

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A molecule that binds to a location on the enzyme apart from the active site (allosteric site), inducing a conformational change in the enzyme and blocking substrate binding

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Noncompetitive/Allosteric inhibitor

A molecule that binds to an allosteric site and causes a conformational change in the enzyme that promotes substrate binding

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