A molecule that binds to an allosteric site and causes a conformational change in the enzyme that promotes substrate binding

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Allosteric activator

Allosteric Inhibition Diagram (Figure 8.9a). Reprinted from OpenStax Microbiology (p. 300), by N. Parker, M. Shneegurt, A.-h. Thi Tu, B. M. Forester, and P. Lister, 2016, Rice University. Copyright 2016 by Rice University.

Allosteric Inhibition Diagram

A molecule that binds to a location on the enzyme apart from the active site (allosteric site), inducing a conformational change in the enzyme and blocking substrate binding

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University of Notre Dame

Some enzyme inhibitors that help regulate enzymatic activity include:

- Competitive inhibitor
- Noncompetitive (allosteric) inhibitor
- Uncompetitive inhibitor

Types of Enzyme Inhibitors

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A molecule similar enough to a substrate so that it binds with the active site and effectively blocks the substrate from binding. To be effective, the inhibitor has to be in equal concentration with the substrate.

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Competitive inhibitor

Noncompetitive/Allosteric inhibitor

The inhibition of enzymatic activity through the metabolic pathway product blocking further pathway action\

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