A molecule similar enough to a substrate so that it binds with the active site and effectively blocks the substrate from binding. To be effective, the inhibitor has to be in equal concentration with the substrate.

(Photo credits in References)

Competitive inhibitor

A molecule that binds to a location on the enzyme apart from the active site (allosteric site), inducing a conformational change in the enzyme and blocking substrate binding

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Noncompetitive/Allosteric inhibitor

The inhibition of enzymatic activity through the metabolic pathway product blocking further pathway action\

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Feedback inhibition

Some enzyme inhibitors that help regulate enzymatic activity include:

- Competitive inhibitor
- Noncompetitive (allosteric) inhibitor
- Uncompetitive inhibitor

University of Notre Dame

A molecule that inhibit enzyme function as a means of regulating its activity

Enzyme Inhibitor

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