Connectivity alterations within brain DMN and FC have been associated with the theory of mind, self-referencing, memory, and rumination 

Alma College

Functional connectivity is a coactivation of anatomically distinct brain regions in temporal patterns. This is negatively correlated with the DMN  and psychometric components that have downstream therapeutic effects. In this regard, a reduction in FC with brain regions that comprise the DMN is related to ego dissolution (Oceanic SelfBoundlessness as measured with proper scales) l that can occur during the psychedelic experience; which in consequence has positive therapeutic effects.

Functional connectivity and DMN connectivity

Gattuso, J. J., Perkins, D., Ruffell, S., Lawrence, A. J., Hoyer, D., Jacobson, L. H., Timmermann, C., Castle, D., Rossell, S. L., Downey, L. A., Pagni, B. A., Galvão-Coelho, N. L., Nutt, D., &amp; Sarris, J. (2022). Default mode network modulation by psychedelics: A systematic review. International Journal of Neuropsychopharmacology, 26(3), 155–188. https://doi.org/10.1093/ijnp/pyac074 

Learn Before

Related