Causes mismatches between codons and anticodons leading to faulty proteins that insert and disrupt the cytoplasmic membrane

University of Southern Mississippi

- Chloramphenicol
- Macrolides
- Lincosamides
- Tetracycline
- Aminoglycosides
- Oxazolidinones

Major classes of Protein Synthesis Inhibitors

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Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

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Binds to the 50S ribosomal subunit to prevent peptide bond formation and stop protein synthesis

Chloramphenicol

Blocks peptide bond formation between amino acids on the ribosomal 50S subunit

Macrolides & Lincosamides

Blocks the binding of tRNA's with the 30S ribosomal subunit

Tetracycline

Aminoglycosides

Interferes with the formation of the initiative complex between 50S and 30S subunits and other factors

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