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Antagonists
Antagonists are psychoactive drugs that operate by blocking or impeding the normal activity of a neurotransmitter at its receptor site. Unlike agonists, they do not activate the receptor but instead prevent the natural neurotransmitter from binding, thereby helping to correct neurotransmitter imbalances associated with certain disorders.
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Ch.3 Biopsychology - Psychology @ OpenStax
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A pharmaceutical company develops a new drug to manage a disorder characterized by the over-activity of a specific neurotransmitter. The drug molecule is shaped to fit perfectly into the neurotransmitter's receptor sites on the postsynaptic neuron. However, when the drug molecule binds to these sites, it does not cause the neuron to fire. Instead, it simply occupies the space, preventing the natural neurotransmitter from binding and exerting its effect. Based on this mechanism, how is this drug best classified?
Schizophrenia Treatment with Dopamine Antagonists