The receptor binding domains (RBDs) of SARS-CoV-2 S protein and the protease domains (PDs) of ACE2 (pink) are changed because of the peptides interacting with the S protein. This prevents the RBD of the S protein of SARS-CoV-2 from connecting to the PD of ACE2. The following peptides interacted with the S1 domain of the viral S protein:

• Mo-CBP3-PepI
• Mo-CBP3-PepII
• Mo-CBP3-PepIII
• RcAlb-PepI
• RcAlb-PepII
• PepGAT
• RcAlb-PepIII

The following peptides interacted with the S2 domain of the viral S protein:

• PepKAA