1Cademy - Case Study: COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features

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Case Study: COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features

The first presumptive case of COVID-19 associated acute necrotizing hemorrhagic (ANE)—related to intracranial cytokine storms, which result in BBB breakdown.
3-day history of cough, fever, and altered mental status
Testing for the presence of SARSCoV-2 in the CSF was unable to be performed
Evidence of ANE:
CT images demonstrated symmetric hypoattenuation within the bilateral medial thalami with a normal CT angiogram and CT venogram (Fig 1).
Images from brain MRI demonstrated hemorrhagic rim enhancing lesionswithin the bilateral thalami, medial temporal lobes, and subinsular regions (Fig 2).