1Cademy - Changes in the brain associated with Depression

Relation

Changes in the brain associated with Depression

Increased blood flow in the pre-frontal cortex and amygdala
Decreased blood flow in the parietal and posterior temporal cortex
Descendants of people with severe depression are shown to have a thinner cortex across the right hemisphere, possibly making them more vulnerable to depression
Reduced volume in the hippocampus of depressed people
However, it is unclear whether these changes in the brain were present before the depression

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Updated 2025-10-08

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