Symptoms of the illness include rapid dehydration, electrolyte imbalance, and diarrhea. 

University of Notre Dame

Vibrio cholerae serotype 1 is a gram-negative, flagellated bacterium shaped like a curved rod (vibrio). The bacteria is easily killed by stomach acid, so large amounts are needed to reach the intestines. 

Cholera Caused by Vibrio cholerae

https://openstax.org/details/books/microbiology/

Microbiology covers the scope and sequence requirements for a single-semester microbiology course for non-majors. The book presents the core concepts of microbiology with a focus on applications for careers in allied health. The pedagogical features of the text make the material interesting and accessible while maintaining the career-application focus and scientific rigor inherent in the subject matter. Microbiology’s art program enhances students’ understanding of concepts through clear and effective illustrations, diagrams, and photographs.

Microbiology is produced through a collaborative publishing agreement between OpenStax and the American Society for Microbiology Press. The book aligns with the curriculum guidelines of the American Society for Microbiology.

OpenStax Microbiology Textbook

Cholera: Signs and Symptoma

The microbial cells move through the mucous layer of the intestines before attaching to epithelial cells and releasing cholera enterotoxin, a A-B toxin associated with adenylate cyclase. The enterotoxin stimulates the increase of cyclic AMP levels, activating chloride channels and releasing ions into the intestinal lumen. An increase in osmotic pressure in the lumen causes water (and electrolytes) to leave the body and enter into the lumen, hence rapid dehydration and electrolyte imbalance.

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