Concept

Comparison of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2 With Other Childhood Inflammatory Diseases

The comparison groups of children from cohorts with other inflammatory diseases included

  • 1132 patients with KD
  • 45 with KD shock syndrome
  • 37 with toxic shock syndrome

Patients with PIMS-TS were generally older than those with KD or KD shock syndrome and had higher white blood cell count, neutrophil count, and CRP, as well as more profound lymphopenia and anemia. They also tended to have lower platelet counts, higher fibrinogen levels, and greater elevation of troponin. Alanine aminotransferase levels and D-dimer levels were similar between those with PIMS-TS and KD and also between those with PIMS-TS and KD shock syndrome. Patients with PIMS-TS tended to be older than those with toxic shock syndrome. Hemoglobin levels were lower, while CRP and alanine aminotransferase levels were higher. Ferritin and troponin results were not available in the toxic shock syndrome group.

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Updated 2020-08-13

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences