Considerable countermeasures effectively controlled the COVID-19 outbreak in Wuhan. 

Special efforts are needed to protect vulnerable populations, including healthcare workers, elderly and children. 

Estimation of unascertained cases has important implications on continuing surveillance and interventions.

University of Michigan - Ann Arbor

In Wuhan, aggressive implementation of nonpharmaceutical interventions (NPIs), including a cordon sanitaire of the city, suspension of public transport, school, and most work, and cancellation of all public events reduced the reproductive number from 3.86 to 0.32 over a 5-week period 

Effects of Countermeasures on the Reproductive Number in Wuhan

Wang, Chaolong, et al. “Evolving Epidemiology and Impact of Non-Pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China.” MedRxiv: the Preprint Server for Health Sciences, doi:https://doi.org/10.1101/2020.03.03.20030593.

Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, China

Individual-level data on 25,961 laboratory-confirmed Covid-19 cases reported through February 18, 2020 were extracted from the municipal Notifiable Disease Report System. 

Based on key events and interventions, the epidemic was divided into four periods: before January 11, January 11-22, January 23 - February 1, and February 2-18. 

They then compared epidemiological characteristics across periods and different demographic groups, and developed a susceptible-exposed-infectious-recovered model to study the epidemic and evaluate the impact of interventions

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