Coronary-artery aneurysms are a common feature of KD, affecting approximately one quarter of patients. However, in a study of 186 pediatric patients with MIS-C in 26 states, coronary-artery aneurysms were only documented in 15 patients (8%).

Bowdoin College

In a study of 186 pediatric patients with MIS-C in 26 states, cardiovascular involvement leading to vasopressor or vasoactive support was observed most frequently in older children and adolescents. About 5% of children with KD in the United States present with cardiovascular shock leading to support, compared with 50% of the MIS-C patients in this study. 

Cardiovascular Involvement Differences Between MIS-C and Kawasaki’s Disease (KD)


Feldstein, L. R., Rose, E. B., Horwitz, S. M., Collins, J. P., Newhams, M. M., Son, M. B., ... Randolph, A. G. (2020). Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. New England Journal of Medicine, 383(4), 334-346. doi:10.1056/nejmoa2021680

https://www.nejm.org/doi/full/10.1056/NEJMoa2021680?query=featured_coronavirus

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