Concept

Development and Course of Substance/Medication-Induced Depressive Disorder

A depressive disorder linked to substance use typically emerges while the individual is actively using the substance or experiencing withdrawal if there is a withdrawal syndrome associated with that substance. Often, the depressive symptoms begin within a few weeks or a month of heavy substance use. Once the substance is stopped (through abstinence), the depressive symptoms usually improve within days to several weeks, depending on the substance's half-life and the presence of withdrawal symptoms. If the symptoms persist beyond the expected withdrawal period (about four weeks) for a specific substance, other potential causes for the depressive mood symptoms should be explored.

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Updated 2023-05-23

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Diagnostic and Statistical Manual (DSM)

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