- Tests pituitary-adrenal function
- Participant is given dexamethasone (synthetic glucocorticoid hormone)
- Cause a decline in the production of adrenal corticosteroids 

Michigan State University

Research has long indicated that individuals with depression often exhibit abnormal levels of cortisol, a key stress hormone released by the neuroendocrine system during the body's fight-or-flight response. Elevated cortisol is particularly prevalent in depressed individuals who have experienced early life trauma, such as childhood abuse or the loss of a parent.

HPA Axis Dysfunction and Cortisol Levels in Depression

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

Behavioral Neuroscience 8th Edition

Dexamethasone Suppression Test

Based on the provided case study, predict a likely finding related to stress hormone levels and explain the physiological reasoning for this prediction, considering the individual's history.

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