Diabetes was the second most prevalent comorbidity in a study conducted in Wuhan, China, comprised of 1,576 COVID-19-infected patients (9.7%, 95% CI 7.2-12.2%).

University of Michigan - Ann Arbor

- Wuhan, China
- Mexico
- Italy
- England
- Saudi Arabia

Diabetes in COVID-19 Patients by Geographic Location

Yang, J., Zheng, Y., Gou, X. et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. International Journal of Infectious Diseases (2020). https://doi.org/10.1016/j.ijid.2020.03.017

Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis

Diabetes in COVID-19 Patients in Wuhan, China

• The primary goal of study was to assess the relationship between obesity, type 2 diabetes, and hypertension with severe COVID-19, in Mexico.

• Data was collected from all over Mexico using the Mexican Institute of Epidemiological Diagnosis and Reference; 18,443 tested negative, 3,844 tested positive, and 1,306 were positive for other respiratory viruses.

• Positive cases were compared to negative cases and those who were positive for other respiratory illnesses.

• Patients who tested positive had a higher proportion of obesity (17.4%), diabetes (14.5%), and hypertension (18.9%).

• Patients with obesity had a 1.43-fold chance of developing severe COVID-19, patients with diabetes had a 1.87-fold chance of developing severe COVID-19, and patients with hypertension had a 1.77-fold chance of developing severe COVID‐19.

• Obesity, diabetes, and hypertension were all significantly related to severe COVID-19 development in comparison to patients without these preexisting conditions.

Diabetes in COVID-19 Patients in Mexico

• The primary objective of this study was to determine the relationship between pre-existing diabetes and in-hospital mortality of COVID-19 patients.

• This study was conducted in the Lombardy region of Italy and the data came from Policlinico di Monza hospital.

• 373 patients were assessed in this study. 

• The mean age of the patients was 72 years and 69 of the 373 patients had pre-existing diabetes.

• It was found that patients with pre-existing diabetes were more commonly associated with hypertension and chronic kidney disease when comparing them to non-diabetic patients.

• It was also found that diabetes was independently associated with an increased in-hospital mortality while hypertension and chronic kidney disease were not. 

• This study demonstrates that in the Lombardy region of Italy, patients with diabetes are at a higher risk of in-hospital mortality than non-diabetic patients.


Diabetes in COVID-19 Patients in Lombardy, Italy

• The objective of this study was to understand the association of COVID-19 related mortality and patients with type 1 or type 2 diabetes in England.

• The data for this study utilized national data and was provided by the National Diabetes Audit.

• The weekly number of deaths of patients with either form of diabetes was recorded for the first 19 weeks of 2020 and the percentage difference in mortality rate from previous years was calculated.

• It was found that 464 people with type 1 diabetes and 10,525 people with type 2 diabetes had COVID-19 related deaths in this 19-week period.

• It was calculated that the mortality rate for the first 19 weeks of 2020 was higher by 50.9% in people with type 1 diabetes and 64.3% in people with type 2 diabetes.

• The study concluded that mortality rates rose sharply in both patients of type 1 and type 2 diabetes during the COVID-19 pandemic in England. 

•This increased mortality was independently associated with diabetes.


Diabetes in COVID-19 Patients in England

- The objective of this study was to analyze comorbidities and associated mortality rates of COVID-19 patients in Saudi Arabia. 

- The data for this study was obtained from a King Salman Hospital in Riyadh, Saudi Arabia and involved 300 patients that were admitted from May 1 to July 31, 2020.

- The most frequent comorbidities were hypertension at 28%, type 2 diabetes mellitus at 45.7%, and most (99%) patients had pneumonia.

- An age of >50 was associated with a 3x greater mortality rate than patients under the age of 50.

- Congestive heart failure and acute kidney injury were also significantly associated with higher mortality.

- Overall, type 2 diabetes was highly prevalent and congestive heart failure and acute kidney injury were associated with mortality among COVID-19 patients in Saudi Arabia.


Learn Before

Related