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Reduced Frontal Lobe Activity in Schizophrenia
Functional brain imaging studies show that many individuals with schizophrenia exhibit less activity in their frontal lobes, especially when performing cognitive tasks. This functional deficit is directly linked to the cognitive symptoms of the disorder, as the frontal lobes are integral to executive functions such as planning, executing behavior, and problem-solving. The reduced neural activation in this region provides a compelling explanation for the difficulties in these functions experienced by patients.
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Behavioral Neuroscience
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Ch.15 Psychological Disorders - Psychology @ OpenStax
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Hypofrontality Hypothesis
A patient diagnosed with schizophrenia participates in a study where they are asked to sort cards according to a specific rule. Partway through the task, the rule for sorting changes. The patient finds it extremely difficult to stop using the old rule and adapt to the new one. This difficulty in planning and mental flexibility is most directly explained by functional imaging studies showing which of the following?