Since school transmission rates of SARS-CoV-2 have been greatly limited by global school closures, the authors suggest we may be underestimating transmission risk among school-aged children when we reopen schools. They propose influenza A could be a potential surrogate marker to estimate the impact of school closure and other prevention strategies for transmission reduction of SARS-CoV-2 among children. They reference Israel, South Korea, and France as examples where officials have closed schools shortly after re-opening due to COVID-19 outbreaks.