Drugs altering presynaptic events
One way drugs can change synaptic transmission is by modifying the behavior of the presynaptic neuron, changing the system that converts an electrical signal (an action potential) into a chemical signal (secretion of neurotransmitter). Most common presynaptic drug effects are:
- effects on transmitter production
- effects on transmitter release
- effects on transmitter clearance
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Drugs altering presynaptic events
Drugs altering postsynaptic events
A new medication is found to alleviate symptoms of a particular disorder by increasing the amount of a specific neurotransmitter available in the synaptic cleft, thereby prolonging its effect. Which of the following is the most plausible mechanism of action for this drug?
A new medication is observed to significantly amplify the signal between two communicating nerve cells, resulting in a stronger and more prolonged response in the receiving cell. Based on the general principles of how substances can affect this communication process, which of the following potential actions is LEAST likely to be the mechanism of this medication?