Concept
E. ACE2 expression in vascular pericytes may affect chemosensory perception causing the loss of smell
(E) Immunostaining for ACE2 protein in the mouse olfactory bulb suggests that vascular pericytes express high level of ACE2 protein
- Pericytes are critical for maintaining the blood-brain barrier, defining local blood pressure, mediating neuroimmune responses
- SARS-CoV-2 attaching vascular pericytes may cause perfusion changes or inflammation that affect chemosensory perception in the brain
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Updated 2020-08-17
Tags
SARS-CoV-2 (COVID-19)
Biomedical Sciences
Related
A. Nasal inflammation in the olfactory clefts caused by SARS-CoV-2 infection
E. ACE2 expression in vascular pericytes may affect chemosensory perception causing the loss of smell
B. Infection of support cells may inhibit olfactory signaling causing OSN death
C. Inflammatory cytokines may also directly or indirectly cause loss of smell
D. SARS-CoV-2 directly infects OSNs causing loss of smell