The study looked at the frequency and patterns of eight reoccurring SARS-CoV-2 mutations in four geographic regions divided by Asia, Oceania, Europe, and North America. RNA-dependent-RNA polymerase mutations were discovered in SARS-CoV-2 spreading throughout Europe, which may have contributed to an overall increased frequency of mutations in this region compared to Asia. 

Summary of Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

Pachetti, M., Marini, B., Benedetti, F. et al. Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant. J Transl Med 18, 179 (2020). https://doi.org/10.1186/s12967-020-02344-6

University of Michigan - Ann Arbor

- Emerging SARS-CoV-2 mutation hot spots include a novel RNA-dependent-RNA polymerase variant

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