Antigen 43 has an alpha43 subunit and a beta43 subunit. Beta43 is the beta barrel subunit. 

Beta barrel proposed structure: alternating hydrophobic and hydrophilic sections on beta sheets that they had observed. There are 18 sheets of them with shorter external loops. 

Structure of Antigen 43

Antigen 43 causes adherence of E.coli and drives flocculation, or cell adhesion. 

Grand Valley State University

Beta barrels are extended beta sheets that form into a roll or a barrel shape. The beta strands are linked with loop structures.

Below is the beta barrel of the human retinol binding protein. PDB ID: 1RBP

Beta Barrels 

Henderson, I. R., & Owen, P. (1999). The major phase-variable outer membrane protein of Escherichia coli structurally resembles the immunoglobulin A1 protease class of exported protein and is regulated by a novel mechanism involving Dam and oxyR. Journal of bacteriology, 181(7), 2132–2141. https://doi.org/10.1128/JB.181.7.2132-2141.1999



The Major Phase-Variable Outer Membrane Protein of Escherichia coli Structurally Resembles the Immunoglobulin A1 Protease Class of Exported Protein and Is Regulated by a Novel Mechanism Involving Dam and OxyR


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