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Concept

Excitatory Neurotransmitters

  • Glutamate and aspartate are the most common
  • Work on NMDA, AMPA, and Kainate ionotropic (ligand-gated ion channels) receptors and metabotropic glutamate receptors (mGluR's)
  • Excitotoxicity (death of neurons when overstimulated due to neural injury such as stroke or trauma) can occur with glutamate

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Updated 2021-06-29

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