- Gamma-aminobutyric acid (GABA) 
- The main inhibitory neurotransmitter in the mammalian nervous system
- GABA receptors are divided to large classes: GABA A (ionotropic), GABA B (metabotropic) , GABA C (ionotropic)

GABA

Rutgers University

- A neurotransmitter that is an amino acid (GABA, glycine, glutamate, aspartate)
- In the brain, amino acid neurotransmitters have the most excitatory and inhibitory neurotransmitters


Amino Acid Neurotransmitters

Breedlove, S. & Watson, N. (2017). Behavioral neuroscience, eighth edition. Oxford University Press.

Behavioral Neuroscience 8th Edition

- Glutamate and aspartate are the most common 
- Work on NMDA, AMPA, and Kainate ionotropic (ligand-gated ion channels) receptors and metabotropic glutamate receptors (mGluR's) 
- Excitotoxicity (death of neurons when overstimulated due to neural injury such as stroke or trauma) can occur with glutamate 

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