Concept
Exercise/PA implications on ACE2 in relation to COVID-19
- randomized, double-blinded, placebo-controlled physical training intervention that lasted 4 weeks
- expression of ACE2 mRNA in skeletal muscle and ACE2 serum concentration in 21 healthy men were measured
- treatment with or without Vitamin C and E in addition to exercise
- results showed an overall increase in ACE2 mRNA expression in skeletal muscle, but a decrease in ACE2 serum concentration
- this implied that the ACE2 mRNA in skeletal muscle does not play a large role in ACE2 serum concentration
- limitations of this study included a small sample and the inability to use ACE2 mRNA measurements to measure ACE2 protein levels
- future research should focus on more directly related COVID-19 tissue with a larger, more diverse cohort
- regardless, it may be beneficial for those who are able to exercise and are at higher risk to incorporate more physical activity in thier daily lives
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Updated 2021-03-06
Tags
SARS-CoV-2 (COVID-19)
Biomedical Sciences