Concept
Immune system and autoimmune diseases from a biochemistry perspective
- When an organism looks tolerance to some of its self-antigens (individual’s immune system’s self – not a foreign substance) causes autoimmune diseases
- Any part of the body can become an antigen, but auto immune diseases are typically linked to certain tissues (image below)
- This tolerance loss the self-antigens may have been caused by a malfunctioning of the mechanism of the immune system to determine itself from a foreign substance. These can be lead on by a trauma or an infection where tissues that are normally free of the immune system are subjected to lymphocytes. i.e. spinal cord
- Auto immune diseases also vary from person to person because of the vast number of possibilities to develop loss of tolerance to self-antigens.
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Updated 2021-04-04
Tags
Biochemistry
Biomedical Sciences