Learn Before
Impact of Comorbidities and Glycemia at Admission and Dipeptidyl Peptidase 4 Inhibitors in Patients With Type 2 Diabetes With COVID-19: A Case Series From an Academic Hospital in Lombardy, Italy
-
The objective of this study was to evaluate the association between type 2 diabetes, plasma glucose levels, and antidiabetic medication on mortality rate in COVID-19 patients.
-
The data for this study was collected from a single center in Lombardy, Italy and involved 379 COVID-19 patients who were admitted between February 20th and April 9th of 2020.
-
90 patients in the study had type 2 diabetes and it was found that the mortality rate in diabetic patients was double that of patients without diabetes.
-
Although after correcting for age and sex, type 2 diabetes was not found to be independently associated with risk of mortality.
-
Elevated levels of plasma glucose and IL-6 were independently associated with higher mortality rates.
-
The use of insulin and β-blockers as antidiabetic medicine were also associated with higher rates of mortality while the use of dipeptidyl peptidase 4 inhibitors was associated with lower mortality rates.
0
1
Tags
SARS-CoV-2 (COVID-19)
Biomedical Sciences