In this study it indicated that 50-80% of patients with Pituitary adenomas will show symptoms and signs of depressive disorder. 

Depressive Disorder in patients with Pituitary adenomas

patients with brain tumors might display certain symptoms such as fatigue and headaches which could be easily misdiagnosed as depression. especially since most of the early diagnosis are shown in patients that are in younger age demographic. 

The study shows that neuropsychological symptoms are the first symptoms that show in patients with brain tumors. 

Neuropsychological symptoms might be the first indicator of brain tumor 

Chieffo, D.P.R.; Lino, F.;
Ferrarese, D.; Belella, D.; Della Pepa,
G.M.; Doglietto, F. Brain Tumor at
Diagnosis: From Cognition and
Behavior to Quality of Life.
Diagnostics 2023, 13, 541.
https://doi.org/10.3390/
diagnostics13030541

patients with brain tumors experience cognitive changes that effects their daily life such as memory issues and motor skill issues.  

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