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Locus Coeruleus

The locus coeruleus is a region located in the brainstem that serves as the brain's primary source of norepinephrine. This neurotransmitter is responsible for activating the body's fight-or-flight response. Research indicates a strong link between this area and anxiety, as its activation is associated with feelings of fear and anxiety. Studies involving nonhuman primates have demonstrated that direct stimulation of the locus coeruleus can induce panic-like symptoms, suggesting its potential role in panic disorder.

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Updated 2025-10-10

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