- was generated by immunization with SARS-CoV antigen
- proved to react with SARS-CoV-2 S2 subunit, but has no neutralizing activity against SARS-CoV-2 virus

State University of New York at Stony Brook

have rarely been reported, but since S2 subunit is more sequentially conserved, it might be helpful to screen for broad S2 specific NAbs
- mAb 1A9

NAbs targeting S2 subunit of spike protein

Huang, Y., Sun, H., Yu, H., Li, S., Zheng, Q., & Xia, N. (2020). Neutralizing antibodies against SARS-CoV-2: current understanding, challenge and perspective. Antibody Therapeutics, 3(4), 285-299.
https://doi.org/10.1093/abt/tbaa028

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