Theory

Mechanism of Discrimination's Health Impact via General Adaptation Syndrome

The process by which chronic discrimination harms health can be modeled by the General Adaptation Syndrome. An initial discriminatory event triggers an acute alarm response. Repeated experiences then lead to a prolonged state of heightened physiological readiness, or resistance. This long-term activation eventually depletes the body's resources, resulting in an exhaustion stage that increases vulnerability to mental and physical health problems such as depression, cardiovascular disease, and cancer.

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Updated 2026-01-15

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