1Cademy - Methods of the Liver Transplant and COVID-19 Study

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Methods of the Liver Transplant and COVID-19 Study

This multicentre cohort study was done by studying two cohorts: liver transplant and no liver transplant.
The data collected for the liver transplant cohort was from known registries online. The data collected for the comparison cohort was from the Oxford University Hospitals National Health Service Foundation Trust in the UK.
Liver injuries were assessed by the patients' peak serum alanine aminotransferase activity and divided into three levels of mild, moderate, and severe injuries. Acute kidney injury was also identified.
Obesity was assumed absent.
White ethnicity was the majority of the transplant cohort and assumed in the comparison cohort.
1:1 propensity score-matched samples were used to analyze the data. The treatment variable was transplantation status and treatment outcome was death. Covariates included age(years), sex, ethnicity, obesity, diabetes, hypertension, and baseline serum creatinine concentration(mg/dL).