Concept

Mortality in Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19

Primary causes:

  • 88% respiratory failure
  • 4% cardiac arrest
  • 8% other cardiopulmonary arrest/multi-organ failure

Multivariable Cox regression model with no drug as reference:

  • treatment with hydroxychloroquine alone decreased mortality hazard ratio 66% (p<0.001) and 71% (p<0.001) with hydroxychloroquine + azithromycin

Significant predictors of mortality:

  • age > 65 years
  • white race
  • lower O2 saturation on admission
  • ventilator use during admission

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Updated 2020-08-07

Tags

SARS-CoV-2 (COVID-19)

Biomedical Sciences