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Neuroadaptation in Severe and Enduring Anorexia Nervosa

Neuroadaptation and resultant habit-forming in anorexia nervosa patients is mediated by the dorsal frontostriatal circuits through repeated behavioral practice of food restriction. Initially, food is intentionally restricted as a means of attaining the positive reinforcement associated with planned weight loss. However, as the illness progresses, caloric restriction becomes automatic and requires little to no effort. Habit reversal therapy can be utilized to reduce the strength of eating disorder habitual behaviors.

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Updated 2024-06-20

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