A study conducted in 2012-2014 revealed that the primary sensory cortices and the amygdala of participants with Autism Spectrum Disorder exhibited stronger activation than the primary sensory cortices and the amygdala of neurotypical participants. The stronger activation in primary sensory cortices and the amygdala in the participants with ASD were strongly correlated with sensory over-responsivity symptoms. The researchers also found differences in the neural habituation to stimuli in sensory cortices and the amygdala between the participants with ASD that have sensory over-responsivity and the participants with ASD that do not have sensory over-responsivity. The participants with ASD and sensory over-responsivity exhibited decreased neural habituation to stimuli in their sensory cortices and their amygdala. The participants with ASD without sensory over-responsivity exhibited amygdala downregulation, with negative connectivity between the amygdala and orbitofrontal cortex.