- Convergent B cell responses to SARS-CoV-2 epitopes are predominantly naive
- Shared T cell clusters emerge over disease course in recovering COVID-19 patients
- A receptor sequence repository from COVID-19 patients is established for public use

Smith College

NGS can sequence 30,000 nucleotides of the viral genome. This method provides insight on environmental monitoring, surveillance testing, and origin of the strain to pinpoint the viral evolution. 

Next Generation Sequencing

Schultheiß, C., Paschold, L., Simnica, D., Mohme, M., Willscher, E., Wenserski, L. V., Binder, M. (2020). Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease. Immunity, 53(2). doi:10.1016/j.immuni.2020.06.024

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