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Other CoVs that Utilize the Human ACE2 Receptor for Entry

  • HCoV‐NL63

  • SARS‐CoV

The receptor binding domain (RBD) of the S protein of these CoVs differ from each other, so it is thought that they utilize different mechanisms to enter host cells. However, it has been observed that the S protein of SARS-CoV-2 is much more similar to that of SARS-CoV than HCoV‐NL63.

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Updated 2020-07-15

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SARS-CoV-2 (COVID-19)

Biomedical Sciences

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